I don’t use a computer for musical purposes. Dumped that years ago.
For use with a computer, I believe it’s the same idea. However, you would be using the Pyramid as a sub sequencer which is then clocked and controlled by your software.
So you would need to connect an output from your computer to the input of the Pyramid, and then treat the computer like an elaborate midi controller.
I’m sure there are many more wonderful ways to do this, but I don’t use a computer for music in any capacity (aside from dragging the Pyramid OS updates to the SD card) So I don’t know those methods. Maybe someone else can help?