Other than the bug above I am not aware of any others that seem relevant to long sequences. I haven’t tried to replicate that bug, so I can’t really verify that that is a bug, though it seems likely that it is from what the poster writes. Just because I am not aware of any more relevant bugs does not mean there aren’t any, of course. I’m no expert.
Depending on how you manage making long and complex Projects (‘songs’) you could run into some ‘issues’ that I think stem from some of Pyramid’s limitations.
I think these mostly boil down to the amount of RAM available really. You are probably aware of Pyramid’s 13000 MIDI event limit. You can quite realistically get up to that limit with long complex Projects. It will depend on how you use your Pyramid. There are ways to mitigate potential issues (e.g. regular saving and power cycling) and tools to help reduce the burden on the memory (e.g. MIDI FX).
I think it is possible to make long and complex Projects on Pyramid, though.